
About

Pure signals. Exosomes refined. The future is autologous.
Cellenis® Exo-ME™
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At Zen Aesthetics and Wellness, we love Cellenis® Exo-ME™ PRP, an autologous system that isolates, concentrates, and purifies extracellular vesicles, including exosomes, directly from your own blood.
Everything we use comes from you. A small blood draw is processed in our office in a closed, sterile system, no donor material, no culture media, no preservatives.
Cellenis® Exo-ME™ reflects your own biology, so there is no risk of immune rejection or allergic reaction to donor material or synthetic material that might stay for years.
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Why patients choose Cellenis®
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100% autologous — prepared entirely from your own blood
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Prepared in-office — start to finish during your visit, in a closed sterile system
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Purified, not just concentrated — dual purification removes cellular debris
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Mechanically activated, not enzymatically, for a cleaner regenerative profile
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One draw, multiple areas — face, neck, décolleté, hands, scalp, and body
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Common applications for Exo-ME™ from Cellenis®
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May improve the appearance of skin texture, tone, and photoaging
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Supports a healthier scalp and the appearance of thicker, fuller hair
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Supports the appearance of smoother texture and more even tone
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As a companion to microneedling, laser, or peel procedures​
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FAQs
What is Exo-ME™ from Cellenis®?
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Cellenis® Exo-ME™ PRP is an autologous system that isolates, concentrates, and purifies extracellular vesicles — including exosomes — from a small sample of your own blood. Exosomes are nanosized vesicles the body uses to carry regenerative signals between cells.
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How does Cellenis® Exo-ME™ work?
Cellenis® Exo-ME™ processes a small blood draw through dual centrifugation and mechanical activation, then a purification step that removes cellular debris — leaving a clean, concentrated preparation of EVs. The whole process happens in a closed, sterile system during your visit.
When are results visible?
Skin texture and hydration often improve within 1–4 weeks, with continued change over several months as tissue remodeling progresses. For hair, many patients see visible improvements in scalp health and the appearance of fuller, thicker hair over time. Individual results vary.
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Who is a good candidate for Exo-ME™ from Cellenis®?
Patients looking for a regenerative option derived entirely from their own biology — particularly those who prefer to avoid donor-derived or synthetic materials. It is also an option for patients who want to support a healthier scalp and maintain fuller-looking hair over time. Your provider will confirm candidacy for your skin type, health history, and goals at consultation.
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Note on terminology: any reference to “exosomes,” “purified exosomes,” or “exosome-rich” is descriptive only. These terms refer to extracellular vesicles (EVs) ≤200 nanometers in diameter, of which exosomes are a subset.
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At Zen Aesthetics we pair Cellenis® Exo-ME™ with microneedling, Rezenerate nano microneedling, Ultra+ ultrasound device for facials and hair treatments, Celluma led light therapy, laser treatments, peels, and Cellenis® Derma PRP)
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Exo-ME™ can be used as a stand alone treatment or with combination treatment plans
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Adding billions of exosomes into a precise area for regeneration the results continue to improve as building blocks are established beneath the skin. Exosomes help rebuild tissue from the inside out.
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The treatment is safe using your own body's source for “autologous exosome treatment with no synthetics. Cellenis® Exo-ME™ treatment at Zen Aesthetics and Wellness in Edmond is a forerunner for regenerative medicine in the community. ​​​​​​​​


